Submission Preparation Checklist

As part of the submission process, authors are required to check off their submission's compliance with all of the following items, and submissions may be returned to authors that do not adhere to these guidelines.

  • The submission has not been previously published, nor is it before another journal for consideration (or an explanation has been provided in Comments to the Editor).
  • The submission file is in Microsoft Word document file format.
  • The manuscript was written using the Journal template file.
  • Please fill in, sign, scan and upload the Covering letter.
  • All the information about the authors should be complete and correctly introduced during the submission step (please check the spelling, affiliation, correct use of Capital Letter, the last name should be in uppercase, valid e-mail addresses for all the authors). Only the authors introduced in metadata of the journal will appear in the electronic systems and indexing databases (journal site, DOAJ, Index Copernicus, etc.).
  • At this moment, we encountered some problems with the submission website. To smooth the submission process: 1. please create your account (if you do not already have one); 2. Send us the manuscript, cover letter, and supplementary file (if any) as attached file at: We will upload the file to your account and open the reviewing process. Thank you for understanding.

Author Guidelines

Aim and Scope

Applied Medical Informatics (Appl Med Inform) publishes mainly high-quality original articles and reviews in the field of medical informatics and applications of information technology in medicine, dentistry and pharmacy; medical, dentistry and pharmacology statistics; clinical and preclinical research that use statistics and informatics approaches; and research methodology. The interdisciplinary areas of the journals are as: Probabilities and statistics, Modelling and Calculus Theory, Software Systems, Organization of calculus systems, Computer Science and Information Technology, Medicine, Dentistry and Pharmacy.

Publishing in Applied Medical Informatics is free of charge. If your work is of good quality and fits the journal scope, we welcome it for peer-reviewing. If you decide to submit your paper, please ease our work by carefully adhering to our journal requirements.

Description of Manuscripts Types

Applied Medical Informatics welcomes manuscripts in the following categories:

  • Research articles will provide a detailed description of scientific findings within the scope of the journal. The manuscript should not exceed 8 printed pages (4400 words including tables and references). This type of articles should contain structured abstract (200-250 words), divided as Aim-Material and Method-Results-Conclusion(s). The manuscript should be organized following IMRAD structure: Introduction, Material and Methods, Results, Discussion, Conclusions, Acknowledgments and References. The manuscript must be formatted according to the guidance below.

  • Reviews will be focused on significantly important topics related to journals’ aim. Reviews should contain unstructured abstract (100 – 150 words), up to five keywords and should incorporate a judicious use of tables, figures, schemes and references.

  • Perspectives will follow the general scope of reviews but will have a focus on future predictions rather than past results.

  • Research Letters will be a short version of a Research Article. The discussion could be integrated into the same section with the results as 'Results and Discussion' section; 'Conclusions and Future Directions' are optional.

  • Editorials and Commentaries will be invited by the Editor to provide focused viewpoints of specific topics of interest. It must be written as continuous text without subheadings.

  • Technology Platform will be invited by the Editor to provide a focused description of state-of-the-art R&D tools, methods and knowledge systems significant to specific topics of interest in medical informatics, medical statistics or research methodology. Could be written as continuous text without subheadings.

Covering letter: Please submit with the manuscript the filled and signed covering letter.

Manuscript Preparation

The manuscript should be written in English (US / UK spell) in a clear, concise and precise style. If you have any questions (regarding manuscript preparation, submission...) or maybe you encounter difficulties during the use of the website, please don't hesitate to ask for help:

Please use the template file when preparing the manuscript. Publishing in Applied Medical Informatics is free, so please ease our work by carefully adhering to our journal requirements.

The research articles must be divided into the following sections:

Title: The title of the article should be precise and brief and must not be more than 15 words. Authors should avoid the use of abbreviations.

Title page: Title page should include paper title, author(s) full name and affiliation, corresponding author(s) names complete affiliation/address, along with phone, fax and email.

Abstract: An abstract of maximum 250 words should be typed on a separate page in a form of a single paragraph and should be written in an informative style (purpose, basic methods, main results and principal conclusions).

Keywords: the content of the paper should be characterized by at least 3 and no more than 5 keywords in English (use MeSH when is appropriate) at the end of the abstract.

Introduction: Provide a context or background for the study (i.e., the nature of the problem and its significance). State the specific purpose or research objective of, or hypothesis tested by, the study or observation at the end of this section.

Give only strictly pertinent references and do not include data or conclusions from the work being reported.

Reference list. References are numbered in the list in the order they first appear in the text. The abbreviation of the journals can be found at: For more information about reference style and format consult National Library of Medicine’s Citing Medicine.

Material and Method: The Methods section should include only information that was available at the time the plan or protocol for the study was written; all information obtained during the conduct of the study belongs in the Results section.

- Technical information. Identify the methods, apparatus (give the manufacturer’s name and address in parentheses), and procedures in sufficient detail to allow other researchers to reproduce the study. Briefly describe for methods that have been published but are not well known (provide also the references). Describe in details new or substantially modified methods, give reasons for using them, and evaluate their limitations.

- Statistics. Describe statistical methods with enough detail to enable a knowledgeable reader with access to the original data to verify the reported results. When possible, quantify findings and present them with appropriate indicators of measurement error or uncertainty (such as confidence intervals). Define statistical terms, abbreviations, and most symbols. Specify the computer software used.

- Results or System developed: Present your results in logical sequence in the text, tables, and illustrations, giving the main or most important findings first. Do not repeat in the text all the data in the tables or illustrations; emphasize or summarize only important observations.

Give numeric results not only as derivatives (for example, percentages) but also as the absolute numbers from which the derivatives were calculated, and specify the statistical methods used to analyze them. Restrict tables and figures to those needed to explain the argument of the paper and to assess its support. Use graphs as an alternative to tables with many entries; do not duplicate data in graphs and tables. Avoid non-technical uses of technical terms in statistics, such as “random” (which implies a randomizing device), “normal,” “significant,” “correlations,” and “sample.”

Discussion: Emphasize the new and important aspects of the study and the conclusions that follow from them. Do not repeat in detail data or other material given in the Introduction or the Results section.

State new hypotheses when warranted, but clearly label them as such.

Conclusion(s): Link the conclusions with the goals of the study but avoid unqualified statements and conclusions not adequately supported by the data.

List of abbreviations (if any)

Ethical Issues (if any): Provide clear statement on the ethical issues if clinical or animal research has been conducted if applied.

Conflict of interest (if any): Conflict of interest statement, patient confidentiality issues, and permissions. Where an author gives no conflict of interest, the listing will read 'The author(s) declare that they have no conflict of interest'.

Authors' Contributions (not compulsory): The contributions of authors to the manuscript should be specified in this section. (Suggestion: AB carried defined the aim of research and the design of the experiment. CD carried out the experiments. EF participated in the design of the study and performed the statistical analysis. GH coordinate and helped to draft the manuscript. All authors read and approved the final manuscript.

Acknowledgements (if any): Please acknowledge anyone (individual/company/institution) who has contributed to the study by making substantial contributions to conception, design, acquisition of data, or analysis and interpretation of data, or who was involved in drafting the manuscript or revising it critically for important intellectual content. Please list the source(s) of funding for the study (if any), for each author, and for the manuscript preparation in the acknowledgements section.

References: References must be listed in the Vancouver Style only. All references should be numbered sequentially [in square brackets] in the text and listed in the same numerical order in the Reference section.


Journal Reference:

Martin JM, Jabot F, Marrel P. How to Organise the Medical Data of Chronically III Patients in the Computer. Meth Inform Med 2001;24:5-12. doi:10.1055/s-0038-1635351 (journal article)

Nicula C, Nicula D, Rednik A, Bulboacă A E, Bolboacă S D. Comparison of Ex-PRESS P-200 mini-shunt implantation and standard trabeculectomy for open-angle glaucoma: four-year follow-up. Archives of Medical Science. 2019. doi:10.5114/aoms.2019.89971 (journal article online first)

Brar HK, Dey S, Bhardwaj S, Pande D, Singh P, Dey S, Ghosh-Roy A. Dendrite regeneration in C. elegans is controlled by the RAC GTPase CED-10 and the RhoGEF TIAM-1. PLoS Genet. 2022;18(3):e1010127. doi:10.1371/journal.pgen.1010127 (electronic journal article)

Cardoso F, Kyriakides S, Ohno S, Penault-Llorca F, Poortmans P, Rubio IT, Zackrisson S, Senkus E; ESMO Guidelines Committee. Early breast cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up†. Ann Oncol. 2019;30(8):1194-1220. doi: 10.1093/annonc/mdz173. Erratum in: Ann Oncol. 2019;30(10):1674. doi: 10.1093/annonc/mdz173. Erratum in: Ann Oncol. 2019;30(10):1674. doi: 10.1093/annonc/mdz189. Erratum in: Ann Oncol. 2021;32(2):284. doi:10.1016/j.annonc.2020.08.2158. (article with eratum)

Martínez-Quintana E, Rossique-Delmas P, Rodríguez-González F. Hipertensión arterial resistente y coartación de aorta [Resistant arterial hypertension and coarctation of the aorta]. Clin Investig Arterioscler. 2014;26(6):293-5. Spanish. doi:10.1016/j.arteri.2014.05.002. (article published in other language than English)

Practice Bulletin No 182: Hereditary Breast and Ovarian Cancer Syndrome. Obstet Gynecol. 2017;130(3):e110-e126. doi:10.1097/AOG.0000000000002296. (article without authors)

Retraction of: Identification of Prognosis Biomarkers of Prostatic Cancer in a Cohort of 498 Patients from TCGA, by Chen Z, Hu H. (J Comput Biol Dec 2019: epub ahead of print; doi:10.1089/cmb.2019.0224).  J Comput Biol. 2020;27(4):673. doi:10.1089/cmb.2019.0224.retract (retraction note)

Book and book chapter Reference:

Fauci AS, Braunwald E, Isselbacher KJ, Wilson JD, Martin JB, Kasper DL, et al, editors. Harrison’s principles of internal medicine. 14th ed. New York: McGraw Hill, Health Professions Division; 1998. (book)

Walker HK, Hall WD, Hurst JW. Clinical Methods. The History, Physical, and Laboratory Examinations. 3rd ed. Boston: Butterworths; [online] 1990 [cited 2011 March 20]. Available from: URL: (electronic book)

Speroff L, Fritz MA. Clinical gynaecologic endocrinology and infertility. 7th ed. Philadelphia: Lippincott Williams and Wilkins; 2005. Chapter 29, Endometriosis; p. 1103-33. (book chapter)

Conference paper:

Bolboacă S, Jäntschi L. Binomial distribution sample confidence intervals estimation for positive and negative likelihood ratio medical key parameters. AMIA Annu Symp Proc. 2005:66-70.


Yousof Ali Abdulla Al-Hammadi. Toxins and Their Phytoremediation Behavioural Correlation for Malicious Bot Detection [PhD thesis]. University of Nottingham; 2010. [cited 2011 March 20] Available from: URL:, 2010.


Atherton J. Behaviour modification [Internet]. 2010 [updated 2010 Feb 10; cited 2011 March 10]. Available from: /learning/behaviour_mod.htm

Supportive/supplementary material (if any)


- Ethical considerations -

Applied Medical Informatics adheres to ethical standards of publishing medical research. Our journal follows the Uniform Requirements for Manuscripts Submitted to Biomedical Journals:

I. Human and animal research

The researches involving humans or animals must have been approved by the authors’ institutional committee(s) board. The board must be named by the authors in the manuscript.

Human research: Informed consent must be obtained (or the reason for lack of consent explained, e.g. the data were analyzed anonymously). All clinical investigation must have been conducted according to the principles expressed in the "Declaration of Helsinki" whenever the research involved human participants. The use of informed consent must be stated in the Methods section (written or oral). If informed consent was oral the following information must be provided in the Methods section: ▪ the reason for the impossibility to obtain the written consent; ▪ the committee board approved the use of oral consent; ▪ the method used to document the consent. Authors should be able to submit, upon request, a statement from the research ethics committee indicating the approval of the research. We also encourage authors to submit a sample of patient consent form as supplementary material.

Animal research: The researches involving animals must be conducted according to national and international rules, regulations and guidelines. Authors must include in Material and Methods section details of animal welfare and steps taken to ameliorate suffering whenever animals were studied. The institution that approved the study must be named, and it must be stated in the paper that the study was conducted adhering to the institution's guidelines for animal research.

II. Patient Privacy and Informed Consent for Publication

According to the Uniform Requirements for Manuscripts Submitted to Biomedical Journals

  • „Patients have a right to privacy that should not be infringed without informed consent. Identifying information … should not be published in written descriptions, photographs, and pedigrees unless the information is essential for scientific purposes and the patient (or parent or guardian) gives written informed consent for publication. Informed consent for this purpose requires that the patient be shown the manuscript to be published.”

  • “Complete anonymity is difficult to achieve, however, and informed consent for publication should be obtained if there is any doubt.” If data is changed to protect anonymity, authors should provide assurance that alterations of the data do not distort scientific meaning.

  • „When informed consent has been obtained it should be indicated in the published article."

Having problems?

If you have any questions (regarding Journal scope, manuscript preparation, submission, or others) or maybe you encounter difficulties during the use of the website, please don't hesitate to ask for help:


- Corrections, Retractions and Expressions of Concern -

Corrections & Retractions

Applied Medical Informatics journal will issue corrections, retraction statements, and other post-publication updates, including Editor’s notes and Expressions of concern on published content.

The following are the possible corrections and post-publication updates to peer-reviewed research and review-type articles: 

  • Author or Publisher correction: After publication, an author or the publisher may ask to correct a critical error(s) made that affects the scientific integrity of the published article, the publication record, or the reputation of the authors or the journal.

  • Author name change: An author may ask name correction when changing their name (for reasons such as gender transition or religious conversion, etc.). The correction can happen silently (no note will flag the change on *.pdf or *.html) or not (formal public author correction).

  • Addendum: An addendum is published whenever additional information critical to the reader’s understanding of the reported data comes to light after the publication of the article.

  • Editor's note: An Editor's note is published whenever Applied Medical Informatics initiates an inquiry in response to concerns of a published article. The Editor's note is available only to the *.html version of the published article, and it is not indexed.

  • Editorial expression of concern: An Editorial expression of concern aims to alert the readers about serious concerns affecting the integrity of a specific paper published by Applied Medical Informatics. It is published online, is linked to the published paper, and is indexed in the scholarly databases.

  • Retraction: Violation of research or publication ethics may result in the retraction of a published manuscript. The *.pdf file of the retracted article remains available to readers but will be appropriately labeled as retracted. The retraction statement will be linked to the original published paper. The assent or dissent from the authors will be asked and if they agreed will be included in the retraction statement.

The Committee on Publication Ethics (COPE) recommends the publication of Editor’s note and Editorial expression of concern to keep readers updated while a potential research integrity investigation is underway. Once the investigation is complete, the Editor’s note and Editorial expression of concern are replaced by publishing another amendment, such as a correction or retraction. 

Published content removal

Applied Medical Informatics, in case of exceptional circumstances (e.g., defamatory content; unlawful - intellectual property right, right to privacy, etc.; a court or government order requirement; etc.), reserves the right to remove (temporary or permanently) an article from journal website. In such cases, a statement explaining why the content has been removed will be linked with the bibliometric metadata of the article.

Advertising policy

  • Editorial decisions are independent of the sponsors and advertisers and will not be led by marketing decisions. The involvement of sponsors and advertisers in the editorial workflow is banned.

  • Applied Medical Informatics reserves the right to decline any advertising for products or services known to be harmful to health (e.g., tobacco, alcohol products, etc.)

  • Applied Medical Informatics does not accept any advertisements in the body of the manuscripts.

  • Details about the advertiser and the information of the product or service being offered will accompany any advertisement. The reliability of the information will be carefully verified before publication. Applied Medical Informatics will not accept indecent or offensive advertisements (in text or artwork), or those with a personal, racial, ethnic, sexual orientation, or religious nature.

  • Applied Medical Informatics reserves the right to decline any advertising with inappropriate content.

  • Editor(s) or Publisher could request to remove from the journal website an advertisement published online.

  • The association of a sponsor or advertiser with a specific article or editorial is not allowed and the link to an article using keywords is not permitted. 

  • Editorial content and advertisements must be distinguishable. Special issues that publish abstracts will not undergo peer review. A peer review process distinct from the journal policy applied in case of special issues should be explicitly stated.

Advertising complaints policy - Please send any complaints about advertising to: