Original Research, Review, Editorial, Perspective, Research Letter, Commentary, Technology Platform, Case study, Communication, Point of view (choose the type of Paper)

Title of the Paper

First name SECOND NAME (FAMILY NAME) 1,*, First name SECOND NAME2, and First name SECOND NAME 3

1 Full Affiliation (Department and Institute) and Full Address (street name, street number, postal code, city, country).

2 Full Affiliation (Department and Institute) and Full Address (street name, street number, postal code, city, country).

3 Full Affiliation (Department and Institute) and Full Address (street name, street number, postal code, city, country).

E-mail(s): author2@email; author2@email; author3@email

* Author to whom correspondence should be addressed; Tel.: …; Fax: …

Received: Day Month Year/Accepted: Day Month Year / Published online: Day Month Year

(to be completed by editor)

Original Research, Review, Editorial, Perspective, Research Letter, Commentary, Technology Platform, Case study, Communication, Point of view (choose the type of Paper)

Title of the Paper

Abstract

An abstract of a maximum of 250 words should be typed on a separate page in the form of a single paragraph and should be written in an informative style (purpose, basic methods, main results, and principal conclusions).

Keywords: Define 4 to up to 5 keywords delimitated; Keyword; Keyword (use MeSH database when you define your keywords)

Introduction

Provide a context or background for the study (e.g., the nature of the problem and its significance). References must support all information included in this section. Give only strictly pertinent references and do not include data or conclusions from the work being reported. References are numbered in the list in the order they first appear in the text. The abbreviation of the journals can be found at: http://www.ncbi.nlm.nih.gov/sites/entrez?db=journals. Please consult the National Library of Medicine’s Citing Medicine for more details.

End this section with the specific aim or research objective(s) of the study.

Materials and Methods

This Is Subsection Heading

Selection and Description of Participants. Describe, if applicable, your selection of the observational or experimental participants (patients or laboratory animals, including controls) clearly, including eligibility and exclusion criteria and a description of the source population.

This Is Subsection Heading

The Methods section should include only information that was available at the time the plan or protocol for the study was written; all information obtained during the conduct of the study belongs in the Results section. Provide in this section sufficient information to allow reproduction of the study.

Technical information. Identify the methods, apparatus (give the manufacturer’s name and address in parentheses), and procedures in sufficient detail to allow other researchers to reproduce the study. Briefly describe methods that have been published but are not well known (also provide references). Describe in detail new or substantially modified methods, give reasons for using them, and evaluate their limitations.

Statistics. Describe, if applicable, statistical methods with enough detail to enable a knowledgeable reader with access to the original data to verify the reported results. When possible, quantify findings and present them with appropriate indicators of measurement error or uncertainty (such as confidence intervals). Define statistical terms, abbreviations, and most symbols. Specify the computer software used.

Results

Present your results logically in the text, tables, and illustrations, first giving the main or most important findings. Do not repeat in the text all the data in the tables or illustrations; emphasize or summarize only important observations.

Give numeric results as derivatives (for example, percentages) and the absolute numbers from which the derivatives were calculated, and specify the statistical methods used to analyze them. Restrict tables and figures to those needed to explain the paper's argument and assess its support. Use graphs as an alternative to tables with many entries; do not duplicate data in graphs and tables. Avoid non-technical uses of technical terms in statistics, such as “random” (which implies a randomizing device), “normal,” “significant,” “correlations,” and “sample.”

Add an equation following the model below.

[add an equation here; use MS Word or MathType equation function]	(1)

This Is Subsection Heading

Main text paragraph.

Main text paragraph.

Table 1. Add a descriptive label for the table here

[add the table here; use MS Word’s table function] [use Garamond 10 in the body of the table]

[add the figure here]

Figure 1. (a) Add a descriptive label of the figure here. (b) Add a descriptive label of the figure here. (c) Add a descriptive label of the figure here

Discussion

Begin the discussion by brieﬂy summarizing the main ﬁndings, and explore possible mechanisms or explanations for these ﬁndings.

Do not duplicate the results but refer to your own results (e.g., see Table x, see Figure y) to support your findings. Emphasize the new and important aspects of your study and put your findings in the context of the totality of the relevant evidence.

State the limitations of your study, and explore the implications of your ﬁndings for future research and for clinical practice or policy. If applicable, discuss the influence or association of variables, such as sex or age, on your findings, where appropriate, and the limitations of the data.

State new hypotheses when warranted, but clearly label them as such.

Conclusions

List in this section only the conclusions supported by your results. Do not include in this section a summary of the paper.

List of Abbreviations: Provide the full list of abbreviations used in the manuscript. If not applicable, please use the following expression: “Not applicable.”

Author Contributions: The contributions of authors to the manuscript should be specified in this section. (Suggestion: AB defined the research's aim and the experiment's design. CD carried out the experiments. EF participated in the design of the study and performed the statistical analysis. GH coordinated and helped to draft the manuscript. All authors read and approved the final manuscript.). The authors' contribution must follow the ICMJE criteria available under Defining the Role of Authors and Contributors.

Funding: Please add: “This research was funded by NAME OF FUNDER, grant number xyz/dd/mm/yyyy”. If you study received no funds, please use the following statement: “This research received no funding.”

Ethics Statement: Whenever applicable, include in this section the information regarding the ethics approval (e.g., name of the Ethics Board, approval number, and approval date). We expected to see information for any study conducted on humans (including those with a retrospective collection of data, excepting secondary use) and animals. Include in this section also information regarding patient confidentiality issues, and permissions, if applicable.

Data Availability Statement: We encourage the authors to share their research data. Please include details regarding where data supporting reported results can be found or accessed in this section, including links to publicly archived datasets analyzed or generated during the study. Where no new data were created, or where data is unavailable due to privacy or ethical restrictions, a statement is still required. If not applicable, please use the following expression: “Not applicable.”

Acknowledgments: Please acknowledge in this section any support given that is not covered by the author's contribution (e.g., administrative or technical support, donations such as materials used for experiments etc.). Please ensure that you have a personal agreement any time when you list names in this section. Also acknowledge, if applicable, the use of any AI tool (e.g., the name and model, version, date of use, and purpose).

Conflict of Interest: The conflict of interest should be listed for each author. If no author have any conflict of interest to report, you the following declaration “The author(s) declare no conflict of interest”. For more details, please consult Disclosure of Financial and Non-Financial Relationships and Activities, and Conflicts of Interest.

References

References must be listed in the Vancouver Style only. All references should be numbered sequentially [in square brackets] in the text and listed in the same numerical order in the References section. Please also provide the DOI whenever available. References by example:

(journal article) Martin JM, Jabot F, Marrel P. How to Organise the Medical Data of Chronically III Patients in the Computer. Meth Inform Med 2001;24:5-12.

(journal article ahead of print) Kim E, Han JY, Moon TJ, Shaw B, Shah DV, McTavish FM, Gustafson DH. The process and effect of supportive message expression and reception in online breast cancer support groups. Psychooncology. 2011 Mar 17. doi: 10.1002/pon.1942.

(book) Fauci AS, Braunwald E, Isselbacher KJ, Wilson JD, Martin JB, Kasper DL, et al. (Eds.) Harrison’s principles of internal medicine. 14th ed. New York: McGraw Hill, Health Professions Division; 1998.

(electronic book) Walker HK, Hall WD, Hurst JW. Clinical Methods. The History, Physical, and Laboratory Examinations. 3rd ed. Boston: Butterworths; [online] 1990 [accessed on 20 March 2011]. Available from: URL: http://www.ncbi.nlm.nih.gov/books/NBK201/

(book chapter) Speroff L, Fritz MA. Clinical gynaecologic endocrinology and infertility. 7th ed. Philadelphia: Lippincott Williams and Wilkins; 2005. Chapter 29, Endometriosis; p. 1103-33.

(article in proceeding) Bolboacă S, Jäntschi L. Binomial distribution sample confidence intervals estimation for positive and negative likelihood ratio medical key parameters. AMIA Annu Symp Proc. 2005:66-70.

(thesis) Yousof Ali Abdulla Al-Hammadi. Toxins and Their Phytoremediation Behavioural Correlation for Malicious Bot Detection [PhD thesis]. University of Nottingham; 2010. [accessed on 2011 March 20] Available from: URL: http://ima.ac.uk/papers/al-hammadi_thesis.pdf, 2010.

(webpage) Atherton J. Behaviour modification [Internet]. 2010 [updated 10 February 2010; accessed on 10 March 2011]. Available from: http://www.learningandteaching.info /learning/behaviour_mod.htm