Prediction of Breast Cancer using Rule Based Classification

Authors

  • Nagendra Kumar SINGH Research Ccholar, Maulana Azad National Institute of Technology Bhopal, India

Keywords:

Chromosome, Mutation, Cancer, Classification, Data Mining, Bioinformatics

Abstract

The current work proposes a model for prediction of breast cancer using the classification approach in data mining. The proposed model is based on various parameters, including symptoms of breast cancer, gene mutation and other risk factors causing breast cancer. Mutations have been predicted in breast cancer causing genes with the help of alignment of normal and abnormal gene sequences; then predicting the class label of breast cancer (risky or safe) on the basis of IF-THEN rules, using Genetic Algorithm (GA). In this work, GA has used variable gene encoding mechanisms for chromosomes encoding, uniform population generations and selects two chromosomes by Roulette-Wheel selection technique for two-point crossover, which gives better solutions. The performance of the model is evaluated using the F score measure, Matthews Correlation Coefficient (MCC) and Receiver Operating Characteristic (ROC) by plotting points (Sensitivity V/s 1- Specificity).

Author Biography

Nagendra Kumar SINGH, Research Ccholar, Maulana Azad National Institute of Technology Bhopal, India

Biological Science and Egineering

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Published

15.12.2015

How to Cite

1.
SINGH NK. Prediction of Breast Cancer using Rule Based Classification. Appl Med Inform [Internet]. 2015 Dec. 15 [cited 2024 Mar. 19];37(4):11-22. Available from: https://ami.info.umfcluj.ro/index.php/AMI/article/view/555

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Section

Articles