Aim: This study aimed to analyze the research activity of Clinical Decision Support Systems (CDSS) for the last two decade via a bibliometric analysis. Material and Method: The search was carried out using the keyword (“clinical decision support system”) in the “topic” selection mode. Documents published between 2000 and 2021 were retrieved from the Web of Science (WoS) database. Bibliometric analysis was performed to assess the quality and quantity of the documents, co-authorship analysis based on countries was employed to analyze the worldwide collaboration pattern in each time-interval, namely 2000-2009, 2010-2019 and 2020-2021. Results: United States of America (USA) ranked first as the most productive country in each time-interval. United Kingdom (UK), USA and China were first-in-line in terms of total citations in each time-interval, respectively. Medical Informatics dominated as the most common research category being listed in top-three in each time-interval. No statistically significant difference was observed between these time-intervals in terms of the number of publications (p=0.433). “Clinical decision support system” was marked as the most frequent authors’ keyword over the years. Conclusion: The usage of CDSSs is expected to prevail more in almost every clinical branch in the next years. Hence, this current study is considered a guide for upcoming and ongoing CDSS research.


Clinical Decision Support System, Bibliometric analysis, Healthcare, Technology, Health-informatics