Dynamics Clinical and Echographic Parameters Evaluation in Patients Prone to Diastolic Dysfunction Occurrence

Abstract

Aim: The assessment of the clinical particularities and evolving echographic parameters evaluation in patients (p) examined in order to find the signs and symptoms corresponding to heart failure (HF), where the initial examination did not reveal echographic criteria of systolic and diastolic function alteration. Material and Methods: 40 patients were selected out of 200 examined, with pathologies frequently met in patients with manifest HF and EF [arterial hypertension (HTA), diabetes mellitus (DM), overweight), excluding the HF patients and the ones with echographic proves of systolic, diastolic function alteration and severe valvulopathies, as well as respiratory disease patients. They also have been clinically examined by echocardiography in the first 3 days from the first examination and then after 3, 6 and 12 months. The patients were divided in two samples, sample A, patients presenting E/A< 1 ratio, at least one examination out of the 4 carried out and sample B with E/A > 1. Results: Assessing the E/A ratio, sample A represents 70% of the patients. Assessing the whole sample, comparing just the first and the last examination highlights E/A < 1 in 35% of patients. E/Ea assessment at septal level shows a significantly difference between the samples, in all 4 examinations. The assessment of cardiac performance parameters (CPP) between the two samples shows a statistically significant difference. Conclusions: The study revealed that the presence of cardiovascular risk factors prepossesses to diastolic dysfunction development, frequently being also associated an alteration of systolic function.