Risk Factors in a Sample of Patients with Advanced Cervical Cancer

Authors

  • Sorina IRIMIE National Institute of Public Health - Regional Centre for Public Health Cluj, Pasteur Street no. 6, 400349, Cluj-Napoca, Romania.
  • Mariana VLAD National Institute of Public Health - Regional Centre for Public Health Cluj, Pasteur Street no. 6, 400349, Cluj-Napoca, Romania.
  • Ileana Maria MIRESTEAN National Institute of Public Health - Regional Centre for Public Health Cluj, Pasteur Street no. 6, 400349, Cluj-Napoca, Romania.
  • Ovidiu BALACESCU “Prof. Dr.I. Chiricuta” Oncology Institute, 34-36 Republicii Street, 400015 Cluj-Napoca, Romania.
  • Meda RUS “Prof. Dr.I. Chiricuta” Oncology Institute, 34-36 Republicii Street, 400015 Cluj-Napoca, Romania.
  • Loredana BALACESCU “Prof. Dr.I. Chiricuta” Oncology Institute, 34-36 Republicii Street, 400015 Cluj-Napoca, Romania.
  • Ioana BERINDAN-NEAGOE “Prof. Dr.I. Chiricuta” Oncology Institute, 34-36 Republicii Street, 400015 Cluj-Napoca, Romania.
  • Rareş BUIGA “Prof. Dr.I. Chiricuta” Oncology Institute, 34-36 Republicii Street, 400015 Cluj-Napoca, Romania.
  • Claudia ORDEANU “Prof. Dr.I. Chiricuta” Oncology Institute, 34-36 Republicii Street, 400015 Cluj-Napoca, Romania.
  • Viorica NAGY “Prof. Dr.I. Chiricuta” Oncology Institute, 34-36 Republicii Street, 400015 Cluj-Napoca, Romania.
  • Alexandru IRIMIE “Prof. Dr.I. Chiricuta” Oncology Institute, 34-36 Republicii Street, 400015 Cluj-Napoca, Romania.

Keywords:

Risk, Cervical cancer, HPV (Human Papilloma Virus), Obesity, Pap smear

Abstract

The estimated burden of neoplasia of uterine cervix in the 27 EU member states sums up to 34300 cases and 16200 death, with higher incidence and mortality in eastern countries. A number of risk factors increase the likelihood of developing cervical cancer. Even if the risk factors significantly increase the chances of developing cervical cancer, a large number of women with risk factors do not develop the disease, and when a woman develops cancer or precancerous lesions in the cervix may be difficult to establish the causal relationship with certain risk factors. The present study aimed to appreciate the presence and magnitude of risk factors for patients diagnosed with advanced cervical cancer and to outline best strategies to reduce the incidence of this neoplasia, and improve prognosis. Risk factors have been investigated in 42 patients diagnosed with advanced cervical cancer using HPV genotyped determination and a questionnaire for the evaluation of cervical cancer risk factors. In our sample of patients a high risk profile is shaping for low socio-economical level, modulated by the impact of HPV infection with high risk stains of virus, overweight-obesity, smoking and inadequate cervical cancer screening. In this frame a special alarm signal is represented by the very high percentage of patients with overweight and obesity. From the public health perspective, we consider that efforts should be focused on preventing weight gain, regular screening and health education field.

Author Biography

Sorina IRIMIE, National Institute of Public Health - Regional Centre for Public Health Cluj, Pasteur Street no. 6, 400349, Cluj-Napoca, Romania.

Department of Medical Informatics and Biostatistics

Assist. Prof., Ph.D., M.Sc., M.D.

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Published

23.12.2011

How to Cite

1.
IRIMIE S, VLAD M, MIRESTEAN IM, BALACESCU O, RUS M, BALACESCU L, BERINDAN-NEAGOE I, BUIGA R, ORDEANU C, NAGY V, IRIMIE A. Risk Factors in a Sample of Patients with Advanced Cervical Cancer. Appl Med Inform [Internet]. 2011 Dec. 23 [cited 2024 Jul. 21];29(4):1-10. Available from: https://ami.info.umfcluj.ro/index.php/AMI/article/view/357

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