Assessment of the Relationship between Hyperlipoproteinemias and Biliary Lithiasis

Abstract

Aim: The purpose of this study was to bring new data regarding the prevalence of biliary lithiasis in Cluj district in regards to the role of hyperlipoproteinemias as a risk factor for this pathology. Material and Method: A clinical study that included 800 adult subjects with age between 18 and 90 was conducted. For each subject an ultrasonographical screening was performed in order to detect biliary lithiasis. The subjects were separated in two subgroups: lithiasic and nonlithiasic. The serum lipids were also determined to all subjects: total cholesterol, tryglicerides, HDL-cholesterol. The levels of serum lipids in the lithiasic and nonlithiasic subgroups were compared. Results: The results showed a higher level of total cholesterol (216.7mg/100ml > 187.6mg/100ml) and triglycerides (203.5mg/100ml > 172.4mg/100ml) in lithiasic subgroup; while the HDL-cholesterol was lower (43.7mg/100ml < 46.2mg/100ml). Comparing the results on both sexes, cholesterol and triglycerides proved to be more elevated in men subgroup, while HDL-cholesterol was smaller in women subgroup. Conclusion: The results lead to the conclusion that in studied area hyperlipoproteinemias are a major risk factor for biliary lithiasis in both sexes.