Antimicrobial Resistance of Staphylococcal Strains Isolated from Various Pathological Products

Authors

  • Laura Mihaela SIMON “Iuliu Haţieganu” University of Medicine and Pharmacy Cluj-Napoca, 13 Emil Isac, 400023 Cluj-Napoca, Romania.
  • Lia Monica JUNIE “Iuliu Haţieganu” University of Medicine and Pharmacy Cluj-Napoca, 13 Emil Isac, 400023 Cluj-Napoca, Romania.
  • Daniela HOMORODEAN Pneumology Clinic Leon Daniello, 6 B.P. Haşdeu, 400371 Cluj-Napoca, Romania.

Keywords:

Resistance, Antibacterial agents, MRSA (methicillin-resistant S. aureus), Staphylococcus.

Abstract

Background: The optimal choice of antimicrobial therapy is an important problem in hospital environment in which the selection of resistant and virulent strains easy occurs. S. aureus and especially MRSA(methicillin-resistant S. aureus) creates difficulties in both treatment and prevention of nosocomial infections. Aim: The purpose of this study is to determine the sensitivity and the resistance to chemotherapy of staphylococci strains isolated from various pathological products. Material and Method: We identified Staphylococccus species after morphological appearance, culture properties, the production of coagulase, hemolisines and the enzyme activity. The susceptibility tests were performed on Mueller-Hinton medium according to CLSI (Clinical and Laboratory Standards Institute). Results: The strains were: MSSA (methicillin-susceptible S. aureus) (74%), MRSA (8%), MLS B (macrolides, lincosamides and type B streptogramines resistance) (12%) and MRSA and MLS B (6%). MRSA strains were more frequently isolated from sputum. MRSA associated with the MLS B strains were more frequently isolated from pus. MLS B strains were more frequently isolated from sputum and throat secretions. All S. aureus strains were susceptible to vancomycin and teicoplanin. Conclusions: All staphylococcal infections require resistance testing before treatment. MLS B shows a high prevalence among strains of S. aureus. The association between MLS B and MRSA remains a major problem in Romania.

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How to Cite

1.
SIMON LM, JUNIE LM, HOMORODEAN D. Antimicrobial Resistance of Staphylococcal Strains Isolated from Various Pathological Products. Appl Med Inform [Internet]. 2011 Jan. 18 [cited 2024 Jul. 20];27(4):74-80. Available from: https://ami.info.umfcluj.ro/index.php/AMI/article/view/25

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