Nowadays, evidence based medicine is used more as a basis of medical practice in all medical specialties. Development of computers sciences and Internet communication allows the development, growing and spread of evidence-based medicine concepts and practice all over the world. We present in this paper some programs used in evidence-based practice in order to create, maintained and up-to-date the best medical reviews,  creating and updating clinical practice guidelines, creating and maintaining critical appraised topics,  storing and retrieving medical information tools, and assessing the health information quality. In order to practice and evidence-based medicine, as physicians, we can choose now the software that is the best for our clinical needs. The conditions are to know English so good that to understand all we read and to be able to write correctly in English and of course to know how to use a computer and how Internet works.


Informatics tools, Evidence-based medicine.