The paper describe the main problems concerning the creating of a client-server application using Borland Delphi environment which are used to find Quantitative Structure – Activity and Structure – Property Relationships using structure descriptors and measured activities/properties for molecules sets stored into a MySQL database server. The described application was used on a set of organic phosphorus herbicides and three new structure-property relationships were resulted and are proposed.


Client - server application, Molecular descriptors family, Multiple linear regression, Relational databases.