Gold and Silver-Decorated Conducting Polymer Coatings with Electroactive, Biocompatible, and Antibacterial Characteristics

Authors

  • Angelika BANAŚ Silesian University of Technology
  • Szymon SMOŁKA Department of Physical Chemistry and Technology of Polymers, Silesian University of Technology
  • Małgorzata SKORUPA Department of Physical Chemistry and Technology of Polymers & Joint Doctoral School, Silesian University of Technology
  • Kaja FOŁTA Department of Physical Chemistry and Technology of Polymers, Silesian University of Technology
  • Kinga BALCERZAK Department of Physical Chemistry and Technology of Polymers, Silesian University of Technology
  • Dawid KROK Department of Physical Chemistry and Technology of Polymers, Silesian University of Technology
  • Divine Yufetar SHYNTUM Biotechnology Centre, Silesian University of Technology
  • Magdalena SKONIECZNA Biotechnology Centre & Department of Systems Biology and Engineering, Faculty of Automatic Control, Electronics and Computer Science, Silesian University of Technology
  • Roman TURCZYN Department of Physical Chemistry and Technology of Polymers & Centre for Organic and Nanohybrid Electronics, Silesian University of Technology
  • Katarzyna KRUKIEWICZ Department of Physical Chemistry and Technology of Polymers, Silesian University of Technology

Keywords:

Conducting polymers, Biocompatibility, Antibacterial properties

Abstract

The formation of multifunctional materials that demonstrate electrochemical capabilities, possess antibacterial attributes, and support cell adhesion stems from ongoing advancements in electrotherapy technologies. A significant challenge lies in formulating a material that can effectively counteract bacterial proliferation without adversely affecting mammalian cells. This study focused on modifying the surface of the conducting polymer, poly(3,4-ethylenedioxythiophene) (PEDOT), by integrating gold and silver particles. The modified PEDOT-Au/Ag surface displayed pronounced selective toxicity against E. coli while preserving its biocompatibility with normal human dermal fibroblasts. The physical characteristics of the PEDOT-Au/Ag surface, including its roughness and wettability, facilitated cell adhesion, while the inclusion of silver particles and the uneven surface contributed to its antibacterial properties. The cytotoxic potential of silver was mitigated through the incorporation of gold particles on the PEDOT surface. Consequently, PEDOT-Au/Ag surface has been identified as an advantageous candidate for enhancing electrotherapeutic applications due to its exceptional biological properties and electroactivity.

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Published

09.05.2024

How to Cite

1.
BANAŚ A, SMOŁKA S, SKORUPA M, FOŁTA K, BALCERZAK K, KROK D, SHYNTUM DY, SKONIECZNA M, TURCZYN R, KRUKIEWICZ K. Gold and Silver-Decorated Conducting Polymer Coatings with Electroactive, Biocompatible, and Antibacterial Characteristics. Appl Med Inform [Internet]. 2024 May 9 [cited 2024 May 29];46(Suppl. S1):S11. Available from: https://ami.info.umfcluj.ro/index.php/AMI/article/view/1001

Issue

Section

Special Issue - RoMedINF