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© Clujul Medical, 2019
Affiliations
Nicolae Miu
”Iuliu Haţieganu” University of Medicine and Pharmacy, Cluj-Napoca
Andreea Liana Răchişan
”Iuliu Haţieganu” University of Medicine and Pharmacy, Cluj-Napoca
Simona Căinap
”Iuliu Haţieganu” University of Medicine and Pharmacy, Cluj-Napoca
Adrian Hruşcă
”Iuliu Haţieganu” University of Medicine and Pharmacy, Cluj-Napoca
Mariana Andreica
”Iuliu Haţieganu” University of Medicine and Pharmacy, Cluj-Napoca
How to Cite
Isoprostanes - the Gold Standard of the Oxidative Stress Assessment in Vivo
Vol 85 No 3 (2012)
Section: Reviews
Pages: 295-297
Abstract
Oxidative stress seems to be involved in the generation and maintenance of several clinical entities. Several in vitro markers of oxidative stress are available, but most are of limited value in vivo because of low sensitivity and/or specificity. Isoprostanes, prostaglandin’s isomers, are a fundamental class of products generated by the oxidative stress reactions. F 2 Isoprostanes are a group of 64 isomeric compounds of prostaglandin F 2α . Determination of F 2 Isoprostanes seems to be the most efficient method to quantify oxidative stress in vivo and has become the gold standard of the assessment of oxidative reactions.