TY - JOUR AU - SIMON, Laura Mihaela AU - JUNIE, Lia Monica AU - HOMORODEAN, Daniela PY - 2011/01/18 Y2 - 2024/03/28 TI - Antimicrobial Resistance of Staphylococcal Strains Isolated from Various Pathological Products JF - Applied Medical Informatics JA - Appl Med Inform VL - 27 IS - 4 SE - Articles DO - UR - https://ami.info.umfcluj.ro/index.php/AMI/article/view/25 SP - 74-80 AB - <p class="Maddress" style="margin-top: 0cm; text-align: justify; line-height: normal;"><em><span style="font-family: Garamond,serif;">Background: </span></em><span style="font-family: Garamond,serif;">The optimal choice of antimicrobial therapy is an important problem in hospital environment in which the selection of resistant and virulent strains easy occurs. S. aureus and especially MRSA(methicillin-resistant S. aureus) creates difficulties in both treatment and prevention of nosocomial infections. <em>Aim: </em>The purpose of this study is to determine the sensitivity and the resistance to chemotherapy of staphylococci strains isolated from various pathological products. <em>Material and Method</em>: We identified Staphylococccus species after morphological appearance, culture properties, the production of coagulase, hemolisines and the enzyme activity. The susceptibility tests were performed on Mueller-Hinton medium according to CLSI (Clinical and Laboratory Standards Institute). <em> Results:</em> The strains were: MSSA (methicillin-susceptible <em>S. aureus</em>) (74%), MRSA (8%), MLS B (macrolides, lincosamides and type B streptogramines resistance) (12%) and MRSA and MLS B (6%). MRSA strains were more frequently isolated from sputum. MRSA associated with the MLS B strains were more frequently isolated from pus. MLS B strains were more frequently isolated from sputum and throat secretions. All <em>S. aureus</em> strains were susceptible to vancomycin and teicoplanin. <em>Conclusions</em>: All staphylococcal infections require resistance testing before treatment. MLS B shows a high prevalence among strains of <em>S. aureus</em>. The association between MLS B and MRSA remains a major problem in Romania.</span></p> ER -