@article{MIHÁLY_BOLBOACA_RĂHĂIAN_BODOLEA_CHIRA_CRISTEA_OBLEZNIUC_MIHÁLY_COMAN_2012, title={Accuracy of Neutrophil Gelatinase-Associated Lipocalin in Detecting Acute Kidney Injury after Urogenital Robotic Assisted Laparoscopic Surgery under General Anesthesia}, volume={30}, url={https://ami.info.umfcluj.ro/index.php/AMI/article/view/380}, abstractNote={<p>The <em>aim</em> of this study was to demonstrate the accuracy of NGAL in detecting Acute Kidney Injury (AKI) after urogenital robotic surgery in general anesthesia. <em>Methods</em>: A prospective longitudinal observational study, which included patients scheduled for elective robotic surgery under general anesthesia. The serum and urine NGAL at induction, 6 hours and 12 hours were determined. Serum creatinine was measured preoperatively and daily 4 days postoperatively. AKI was defined as the absolute growth of serum creatinine by 0.3 mg/dl over baseline within 48 hours postoperatively. <em>Results</em>: 24 patients were enrolled in the study. AKI occurred in 38% of patients. Serum NGAL increased significantly at 6 hours and 12h, compared to baseline, with a higher increase in the group of patents without AKI. There were no significant results for urine NGAL. A link was observed between the values of serum NGAL, with associated significance p<0.0001. The correlations between urine NGAL were not significant. The predictive value of NGAL, analyzed by cross-tabulation, OR was 3 for baseline value and 5.33 for the values measured at 6 hours and 12 hours, but with no statistical significance. <em>Conclusions</em>: The modifications of the NGAL levels, measured at 6 hours and 12 hours from the induction of anesthesia, were significant with more importance at 6 hours and in patients without AKI. Serum NGAL had no predictive value for AKI, but the risk to develop AKI was 3 times higher for baseline determination and 5 times at 6 and 12 hours.<strong><br /></strong></p>}, number={2}, journal={Applied Medical Informatics}, author={MIHÁLY, Orsolya and BOLBOACA, Sorana D. and RĂHĂIAN, Rodica and BODOLEA, Constantin and CHIRA, Cipriana and CRISTEA, Tudor and OBLEZNIUC, Ana and MIHÁLY, Zoltán A. and COMAN, Ioan}, year={2012}, month={Jun.}, pages={47–56} }