Applied Medical Informatics 2003;12(1-2): 3-8.
Bioinformatics and Genome Based Medicine
Tudor Drugan*, Cristina Drugan**, Gheorghe Jebeleanu**, Andrei Achimaş*, Ştefan Ţigan*
* Dept. of Medical Informatics and Biostatistics, University of Medicine and Pharmacy „Iuliu Haţieganu” Cluj-Napoca & ** Dept. of Medical Biochemistry, University of Medicine and Pharmacy „Iuliu Haţieganu” Cluj-Napoca
Abstract
Recent years have witnessed an explosive growth in biological data. Large sequencing projects are producing increasing quantities of nucleotide sequences. The contents of nucleotide databases are doubling in size approximately every 14 months. The latest release of GenBank exceeded one billion base pairs. Not only the size of sequence data is rapidly increasing, but also the number of characterized genes from many organisms and protein structures doubles about every two years. To cope with this great quantity of data, a new scientific discipline has emerged: bioinformatics, biocomputing or computational biology.
Keywords: Bioinformatics; biocomputing; DNA; Nucleotide sequence; Ggenomics; Proteomics.